Prenatal sonographic findings of Klippel-Trénaunay-Weber syndrome

J Clin Ultrasound. 2007 Sep;35(7):409-12. doi: 10.1002/jcu.20323.

Abstract

We describe the prenatal sonographic findings in a case of Klippel-Trénaunay-Weber syndrome including fetal ascites and subcutaneous cystic lesions associated with a relatively low level of maternal serum alpha-fetoprotein and a relatively high level of maternal serum beta-human chorionic gonadotrophin. Klippel-Trénaunay-Weber syndrome may present prenatally with fetal ascites and an abnormal maternal serum screening result in addition to fetal limb hypertrophy and subcutaneous cystic lesions.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Ascites / complications
  • Ascites / diagnosis
  • Chorionic Gonadotropin, beta Subunit, Human / blood
  • Female
  • Hemangioma / complications*
  • Hemangioma / diagnosis
  • Humans
  • Hypertrophy
  • Klippel-Trenaunay-Weber Syndrome / complications
  • Klippel-Trenaunay-Weber Syndrome / diagnosis*
  • Leg / pathology
  • Pregnancy
  • Rare Diseases
  • Skin Neoplasms / complications*
  • Skin Neoplasms / diagnosis
  • Ultrasonography, Prenatal / methods*
  • alpha-Fetoproteins / analysis

Substances

  • Chorionic Gonadotropin, beta Subunit, Human
  • alpha-Fetoproteins