Pneumocystis pneumonia in a patient with non-small cell lung cancer (NSCLC) treated with pemetrexed containing regimen

Lung Cancer. 2007 Aug;57(2):240-2. doi: 10.1016/j.lungcan.2007.02.010. Epub 2007 Apr 2.

Abstract

Pneumocystis pneumonia is typically life-threatening in immunocompromised patients. It is relatively uncommon in patients with lung cancer. We report a case of pneumocystis pneumonia in a patient with advanced stage non-small cell lung cancer (NSCLC) following treatment with concurrent chemoradiation with a pemetrexed containing regimen. To our knowledge, this is the first report on pneumocystis pneumonia following administration of pemetrexed containing regimen.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Antimetabolites, Antineoplastic / therapeutic use*
  • Bronchoscopy
  • Carcinoma, Non-Small-Cell Lung / diagnostic imaging
  • Carcinoma, Non-Small-Cell Lung / drug therapy*
  • Carcinoma, Non-Small-Cell Lung / radiotherapy
  • Fatal Outcome
  • Glutamates / therapeutic use*
  • Guanine / analogs & derivatives*
  • Guanine / therapeutic use
  • Humans
  • L-Lactate Dehydrogenase / blood
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / radiotherapy
  • Male
  • Pemetrexed
  • Pneumonia, Pneumocystis / complications*
  • Pneumonia, Pneumocystis / diagnosis
  • Pneumonia, Pneumocystis / drug therapy
  • Pneumonia, Pneumocystis / surgery
  • Radiography

Substances

  • Anti-Bacterial Agents
  • Antimetabolites, Antineoplastic
  • Glutamates
  • Pemetrexed
  • Guanine
  • L-Lactate Dehydrogenase