No abstract available
Publication types
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News
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Cell Cycle Proteins
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Cell Transformation, Neoplastic / genetics*
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Cellular Senescence / genetics
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Cyclin D
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Cyclin-Dependent Kinases / physiology
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Cyclins / physiology
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DNA Damage
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Eye Neoplasms / drug therapy
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Eye Neoplasms / genetics*
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Genes, Retinoblastoma*
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Genes, p16
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Genes, p53*
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Humans
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Imidazoles / administration & dosage
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Imidazoles / pharmacology
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Mice
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Models, Biological
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Nuclear Proteins / physiology
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Piperazines / administration & dosage
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Piperazines / pharmacology
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Proto-Oncogene Proteins / physiology
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Proto-Oncogene Proteins c-mdm2 / antagonists & inhibitors
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Proto-Oncogene Proteins c-mdm2 / physiology
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Retinoblastoma / drug therapy
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Retinoblastoma / genetics*
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Retinoblastoma Protein / physiology*
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Topotecan / administration & dosage
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Tumor Suppressor Protein p14ARF / physiology
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Tumor Suppressor Protein p53 / physiology*
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Xenograft Model Antitumor Assays
Substances
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Cell Cycle Proteins
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Cyclin D
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Cyclins
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Imidazoles
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MDM4 protein, human
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Nuclear Proteins
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Piperazines
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Proto-Oncogene Proteins
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Retinoblastoma Protein
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Tumor Suppressor Protein p14ARF
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Tumor Suppressor Protein p53
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nutlin 3
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Topotecan
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MDM2 protein, human
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Mdm2 protein, mouse
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Proto-Oncogene Proteins c-mdm2
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Cyclin-Dependent Kinases