The role of academia and the research community in assisting the Food and Drug Administration to ensure U.S. drug safety

Pharmacoepidemiol Drug Saf. 2007 Jul;16(7):818-25. doi: 10.1002/pds.1398.

Abstract

Purpose: Academia can play a prominent role in the drug safety arena, unique from that of industry, and a clearer articulation of how it could positively influence the current system is needed. We sought to examine ways that academia could expand its role in U.S. drug safety.

Methods: An ad hoc meeting of academic experts in drug safety and risk management was convened at the Institute of Medicine (IOM) in Washington, D.C.

Results: Academia should develop a stronger partnership with the Food and Drug Administration (FDA) to increase research on regulatory issues and public health questions and facilitate the prioritization of critical issues on drug safety. Such a collaboration could also facilitate the development of a network of academic centers of excellence in pharmacoepidemiology to address drug safety and risk management questions from a public health standpoint in a timely fashion. The development and testing of methodologic innovations on drug safety should also be encouraged.

Conclusions: Greater partnership between academia and the FDA could facilitate the prioritization of important issues on drug safety, allow more research questions on drug safety to be answered in a timely fashion, promote the development of networks for answering these questions, and help generate additional research ideas, ultimately providing enormous benefit to the public health.

MeSH terms

  • Conflict of Interest
  • Cooperative Behavior*
  • Drug-Related Side Effects and Adverse Reactions*
  • Humans
  • Interinstitutional Relations*
  • Legislation, Drug / organization & administration
  • National Academies of Science, Engineering, and Medicine, U.S., Health and Medicine Division
  • Pharmacoepidemiology / organization & administration
  • Policy Making
  • Public Health
  • Research / organization & administration
  • Risk Management / methods*
  • Safety
  • United States
  • United States Food and Drug Administration / organization & administration*
  • Universities / organization & administration*