The A467T and W748S POLG substitutions are a rare cause of adult-onset ataxia in Europe

Brain. 2007 Apr;130(Pt 4):E69; author reply E70. doi: 10.1093/brain/awm009.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Adult
  • Age of Onset
  • Ataxia / genetics*
  • DNA Polymerase gamma
  • DNA, Mitochondrial / genetics
  • DNA-Directed DNA Polymerase / genetics*
  • Exons / genetics
  • Gene Rearrangement
  • Heterozygote
  • Humans
  • Mutation / genetics

Substances

  • DNA, Mitochondrial
  • DNA Polymerase gamma
  • DNA-Directed DNA Polymerase
  • POLG protein, human