TB-infected deer are more closely related than non-infected deer

Biol Lett. 2007 Feb 22;3(1):103-5. doi: 10.1098/rsbl.2006.0547.

Abstract

Identifying mechanisms of pathogen transmission is critical to controlling disease. Social organization should influence contacts among individuals and thus the distribution and spread of disease within a population. Molecular genetic markers can be used to elucidate mechanisms of disease transmission in wildlife populations without undertaking detailed observational studies to determine probable contact rates. Estimates of genealogical relationships within a bovine tuberculosis-infected white-tailed deer (Odocoileus virginianus) population indicated that infected deer were significantly more closely related than non-infected deer suggesting that contact within family groups was a significant mechanism of disease transmission. Results demonstrate that epidemiological models should incorporate aspects of host ecology likely to affect the probability of disease transmission.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Deer / genetics
  • Deer / microbiology*
  • Female
  • Microsatellite Repeats
  • Mycobacterium bovis*
  • Tuberculosis / transmission
  • Tuberculosis / veterinary*