Oxidative aromatization of Hantzsch 1,4-dihydropyridines in the presence of mixed-addenda vanadomolybdophosphate heteropolyacid, H6PMo9V3O40

Majid M Heravi; Fatemeh Derikvand; Shahla Hassan-Pour; Khadijeh Bakhtiari; Fatemeh F Bamoharram; Hossein A Oskooie

doi:10.1016/j.bmcl.2007.04.002

Oxidative aromatization of Hantzsch 1,4-dihydropyridines in the presence of mixed-addenda vanadomolybdophosphate heteropolyacid, H6PMo9V3O40

Bioorg Med Chem Lett. 2007 Jun 15;17(12):3305-9. doi: 10.1016/j.bmcl.2007.04.002. Epub 2007 Apr 6.

Authors

Majid M Heravi¹, Fatemeh Derikvand, Shahla Hassan-Pour, Khadijeh Bakhtiari, Fatemeh F Bamoharram, Hossein A Oskooie

Affiliation

¹ Department of Chemistry, School of Sciences, Azzahra University, Vanak, Tehran, Iran. [email protected]

PMID: 17452103
DOI: 10.1016/j.bmcl.2007.04.002

Abstract

A variety of Hantzsch 1,4-dihydropyridines were oxidized to the corresponding pyridines in high yields in the presence of H(6)PMo(9)V(3)O(40), a Keggin type heteropolyacid, in refluxing acetic acid. The heteropolyacid was found to be reusable.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Calcium Channel Blockers / chemical synthesis
Calcium Channel Blockers / pharmacology*
Dihydropyridines / chemical synthesis
Dihydropyridines / pharmacology*
Humans
Hydrocarbons, Aromatic / chemistry*
Models, Chemical
Molybdenum / chemistry*
Organophosphorus Compounds / chemistry*
Oxidation-Reduction
Stereoisomerism
Vanadium Compounds / chemistry*

Substances

Calcium Channel Blockers
Dihydropyridines
Hydrocarbons, Aromatic
Organophosphorus Compounds
Vanadium Compounds
1,4-dihydropyridine
Molybdenum