[Filling the thymic space after treatment of Hodgkin's disease: rebound or relapse]

J Margery; T de Revel; E Magois; G Bonardel; I Leduc; P Saint-Blancard; A Bonnichon; F Vaylet; R Jancovici; G Nedellec

doi:10.1016/s0761-8417(07)90089-9

[Filling the thymic space after treatment of Hodgkin's disease: rebound or relapse]

Rev Pneumol Clin. 2007 Feb;63(1):45-7. doi: 10.1016/s0761-8417(07)90089-9.

[Article in French]

Authors

J Margery¹, T de Revel, E Magois, G Bonardel, I Leduc, P Saint-Blancard, A Bonnichon, F Vaylet, R Jancovici, G Nedellec

Affiliation

¹ Service de Pneumologie, HIA Percy, Clamart. [email protected]

PMID: 17457284
DOI: 10.1016/s0761-8417(07)90089-9

Abstract

We report the case of a 36-year-old women with Hodgkin's disease treated with polychemotherapy and bone marrow autograft. Progressive growth of a thymic mass suggested possible relapse four months after treatment withdrawal. This mass did not exhibit gallium-67 uptake but showed strong affinity for 18-FDG (SUV=6.8). Surgical biopsy ruled out recurrence of Hodgkin's disease of the thymus and led to the diagnosis of thymic rebound. The aspect of the thymic compartment returned to normal spontaneously at one year.

Publication types

Case Reports

MeSH terms

Adult
Antineoplastic Combined Chemotherapy Protocols / administration & dosage
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Biopsy
Bone Marrow Transplantation
Female
Follow-Up Studies
Hodgkin Disease / drug therapy
Hodgkin Disease / therapy*
Humans
Positron-Emission Tomography
Radiography, Thoracic
Remission Induction
Thymus Hyperplasia* / diagnostic imaging
Thymus Hyperplasia* / etiology
Thymus Hyperplasia* / pathology
Time Factors
Tomography, X-Ray Computed
Transplantation, Autologous
Whole Body Imaging