Abstract
This study described the expression of betaE-globin in newborns heterozygous for HbE. Despite the lower level of HbE, the pattern of betaE-globin gene expression was similar to betaA-globin because the increase in HbE and HbA reached the peak level at the same time. A delayed decline of HbF was observed.
Publication types
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Letter
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Research Support, Non-U.S. Gov't
MeSH terms
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Age Factors
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Chromatography, High Pressure Liquid
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Female
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Fetal Blood / chemistry
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Fetal Hemoglobin / analysis
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Follow-Up Studies
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Gene Expression Regulation
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Globins / biosynthesis
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Globins / genetics*
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Hemoglobin A / analysis
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Hemoglobin E / analysis
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Hemoglobin E / biosynthesis
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Hemoglobin E / genetics*
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Hemoglobins, Abnormal / analysis
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Hemoglobins, Abnormal / genetics
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Hemoglobinuria / genetics*
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Heterozygote
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Humans
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Infant, Newborn
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Male
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Thailand / epidemiology
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alpha-Thalassemia / genetics*
Substances
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Hemoglobins, Abnormal
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Globins
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Hemoglobin A
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Hemoglobin E
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Fetal Hemoglobin
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hemoglobin Bart's