The compliance, true positive and false negative rates of the Charing Cross protocol for magnetic resonance imaging screening for cerebellopontine angle lesions

J Laryngol Otol. 2008 Mar;122(3):255-8. doi: 10.1017/S0022215107007372. Epub 2007 May 14.

Abstract

Objectives: To assess the effectiveness and determine the compliance to a local protocol for requesting magnetic resonance imaging scans to screen for the presence of cerebellopontine angle lesions.

Methods: A combined retrospective study of all patients who had magnetic resonance imaging scans requested six months prior to and one year following introduction of the protocol and assessment of the true positive and false negative rate of the protocol by assessment of its sensitivity in cases referred from outside the department.

Results: Comparison of the number of scans in each period showed a reduction in annualised rate of 142 to 46. The incidence of positive scans was the same in both periods, increasing the true positive rate from 1.4 to 4.3 per cent. The false negative rate was 1.1 per cent.

Conclusions: The Charing Cross protocol has a good compliance rate within the department, has reduced the cost of screening for cerebellopontine angle lesions and has an acceptable true positive and false negative rate.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Audiometry / methods
  • Cerebellar Diseases / diagnosis*
  • Cerebellopontine Angle / pathology*
  • False Negative Reactions
  • False Positive Reactions
  • Female
  • Humans
  • Magnetic Resonance Imaging / standards
  • Magnetic Resonance Imaging / statistics & numerical data*
  • Male
  • Middle Aged
  • Neuroma, Acoustic / diagnosis
  • Predictive Value of Tests
  • Referral and Consultation
  • Retrospective Studies
  • Treatment Outcome