Managing multiple and extensively drug-resistant tuberculosis and HIV

Expert Opin Pharmacother. 2007 Jun;8(8):1035-7. doi: 10.1517/14656566.8.8.1035.

Abstract

Global increases in multi-drug-resistant and extensively drug-resistant tuberculosis (TB), are threatening both TB and HIV treatment programs worldwide. Together, they raise concerns of a global epidemic of untreatable TB. In the developing world, the directly observed treatment, short course (DOTS) strategy is proving ineffective as available resources are being outstripped by the large number of patients needing treatment. Thus, TB treatment and outcomes are sub-optimal, and multi-drug resistant and extensively drug-resistant TB are on the rise.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Anti-HIV Agents / therapeutic use
  • Antitubercular Agents / therapeutic use*
  • Developing Countries
  • Directly Observed Therapy
  • Disease Outbreaks
  • Drug Resistance, Bacterial
  • Drug Resistance, Multiple
  • Global Health
  • HIV Infections / complications
  • HIV Infections / drug therapy*
  • HIV Infections / epidemiology
  • Health Personnel
  • Humans
  • Prevalence
  • Treatment Outcome
  • Tuberculosis, Multidrug-Resistant / complications
  • Tuberculosis, Multidrug-Resistant / drug therapy*
  • Tuberculosis, Multidrug-Resistant / epidemiology

Substances

  • Anti-HIV Agents
  • Antitubercular Agents