N822 mutation of KIT gene was frequent in pediatric acute myeloid leukemia patients with t(8;21) in Japan: a study of the Japanese childhood AML cooperative study group

Leukemia. 2007 Oct;21(10):2218-9. doi: 10.1038/sj.leu.2404766. Epub 2007 May 24.

Authors

A Shimada, T Taki, C Kubota, T Itou, A Tawa, K Horibe, M Tsuchida, R Hanada, I Tsukimoto, Y Hayashi; Japanese childhood AML cooperative study group

PMID: 17525721
DOI: 10.1038/sj.leu.2404766

No abstract available

Publication types

Letter

MeSH terms

Bone Marrow Cells / metabolism
Child
Chromosomes, Human, Pair 21*
Chromosomes, Human, Pair 8*
Exons
Humans
Japan
Leukemia, Myeloid, Acute / ethnology
Leukemia, Myeloid, Acute / genetics*
Leukemia, Myeloid, Acute / pathology*
Mutation*
Oncogenes
Protein Structure, Tertiary
Proto-Oncogene Proteins c-kit / genetics*
Proto-Oncogene Proteins c-kit / physiology*
Remission Induction
Translocation, Genetic*

Substances

Proto-Oncogene Proteins c-kit