The value of 99mTc-MDP bone scintigraphy in staging primary lymphoma of bone

Nucl Med Commun. 2007 Jul;28(7):529-31. doi: 10.1097/MNM.0b013e3281e2c861.

Abstract

Aim: To assess the value of (99m)Tc-MDP bone scintigraphy in the staging of primary bone lymphoma.

Materials and methods: Thirteen staging scintigrams of patients with biopsy proven primary bone lymphoma were reviewed. The number and location of involved sites of disease were documented in each case.

Results: Seven out of 13 scintigrams (54%) demonstrated a single site of bone involvement. Six cases (46%) showed multifocal disease, including clinically silent weight-bearing sites.

Conclusions: Bone scintigraphy is a valuable tool in the staging of primary bone lymphoma. It detects multifocal involvement which alters prognosis and possibly treatment. Clinically silent involvement of weight-bearing sites may be detected allowing prophylactic treatment if required.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Bone Neoplasms / diagnostic imaging*
  • Bone Neoplasms / pathology*
  • Humans
  • Image Enhancement / methods*
  • Lymphoma / diagnostic imaging*
  • Lymphoma / pathology*
  • Male
  • Neoplasm Staging / methods*
  • Radionuclide Imaging
  • Radiopharmaceuticals
  • Technetium Tc 99m Medronate*

Substances

  • Radiopharmaceuticals
  • Technetium Tc 99m Medronate