Abstract
A matched case-control study was performed to evaluate the risk factors for and outcomes of healthcare-associated infection due to extended-spectrum beta-lactamase-producing Escherichia coli or extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in Thailand. By multivariable analysis, prior exposure to third-generation cephalosporins and transfer from another hospital were risk factors associated with infection. Receipt of inadequate antimicrobial therapy was a predictor of mortality.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Case-Control Studies
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Cross Infection / drug therapy
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Cross Infection / microbiology*
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Cross Infection / mortality
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Escherichia coli / enzymology*
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Escherichia coli / isolation & purification
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Escherichia coli Infections / drug therapy
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Escherichia coli Infections / microbiology*
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Escherichia coli Infections / mortality
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Female
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Humans
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Klebsiella Infections / drug therapy
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Klebsiella Infections / microbiology*
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Klebsiella Infections / mortality
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Klebsiella pneumoniae / enzymology*
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Klebsiella pneumoniae / isolation & purification
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Male
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Middle Aged
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Risk Factors
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Thailand / epidemiology
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beta-Lactam Resistance
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beta-Lactamases / biosynthesis*
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beta-Lactamases / metabolism