Bone formation in elastase-induced rabbit aneurysms embolized with platinum coils: report of 2 cases

AJNR Am J Neuroradiol. 2007 Jun-Jul;28(6):1176-8. doi: 10.3174/ajnr.A0507.

Abstract

Histologic findings in 71 elastase-induced rabbit aneurysms embolized with platinum coils were retrospectively reviewed. Mature bone formation was found in 2 aneurysms, one with coils implanted for 3 months and the other with coils implanted for 1 year. We present the histologic findings and offer potential explanations for these observations. These findings may be relevant in understanding mechanisms of aneurysm healing after coil embolization.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Bone and Bones / pathology*
  • Choristoma / diagnosis
  • Choristoma / etiology*
  • Embolization, Therapeutic / adverse effects*
  • Embolization, Therapeutic / methods
  • Intracranial Aneurysm / chemically induced*
  • Intracranial Aneurysm / complications
  • Intracranial Aneurysm / therapy*
  • Metaplasia / diagnosis
  • Metaplasia / etiology
  • Pancreatic Elastase
  • Rabbits

Substances

  • Pancreatic Elastase