Management of renal tumors by image-guided radiofrequency ablation: experience in 105 tumors

Cardiovasc Intervent Radiol. 2007 Sep-Oct;30(5):936-42. doi: 10.1007/s00270-007-9090-x. Epub 2007 Jun 18.

Abstract

Aims: In this article we present our experience with radiofrequency ablation (RFA) in the treatment of 105 renal tumors.

Materials and methods: RFA was performed on 105 renal tumors in 97 patients, with a mean tumor size of 32 mm (11-68 mm). The mean patient age was 71.7 years (range, 36-89 years). The ablations were carried out under ultrasound (n = 43) or CT (n = 62) guidance. Imaging follow-up was by contrast-enhanced CT within 10 days and then at 6-monthly intervals. Multivariate analysis was performed to determine variables associated with procedural outcome.

Results: Eighty-three tumors were completely treated at a single sitting (79%). Twelve of the remaining tumors were successfully re-treated and a clinical decision was made not to re-treat seven patients. A patient with a small residual crescent of tumor is under follow-up and may require further treatment. In another patient, re-treatment was abandoned due to complicating pneumothorax and difficult access. One patient is awaiting further re-treatment. The overall technical success rate was 90.5%. Multivariate analysis revealed tumor size to be the only significant variable affecting procedural outcome. (p = 0.007, Pearson chi(2)) Five patients had complications. There have been no local recurrences.

Conclusion: Our experience to date suggests that RFA is a safe and effective, minimally invasive treatment for small renal tumors.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Catheter Ablation* / adverse effects
  • Female
  • Follow-Up Studies
  • Humans
  • Kidney Neoplasms / diagnostic imaging
  • Kidney Neoplasms / surgery*
  • Male
  • Middle Aged
  • Radiography, Interventional / adverse effects
  • Radiography, Interventional / methods*
  • Reoperation
  • Time Factors
  • Tomography, X-Ray Computed* / adverse effects
  • Treatment Outcome
  • Ultrasonography, Interventional* / adverse effects