Prevention of de novo hepatitis B virus infection by vaccination and high hepatitis B surface antibodies level in children receiving hepatitis B virus core antibody-positive living related donor liver: case reports

Transplant Proc. 2007 Jun;39(5):1511-2. doi: 10.1016/j.transproceed.2006.11.013.

Abstract

Transmission of hepatitis B virus (HBV) infection from donors negative for hepatitis B surface antigen (HBsAg) but positive for antibody to hepatitis B core antigen (anti-HBc) have been reported. The aim of our study was to evaluate the outcomes of recipients who received liver grafts from living related donors with serological evidence of previous exposure to hepatitis B virus (HBsAg-negative/anti-HBc-positive) after recipient vaccination against HBV before and after liver transplantation.

MeSH terms

  • Child
  • Child, Preschool
  • Hepatitis B / immunology
  • Hepatitis B / prevention & control*
  • Hepatitis B Surface Antigens / immunology*
  • Hepatitis B Vaccines*
  • Humans
  • Infant
  • Liver Transplantation / immunology*
  • Living Donors

Substances

  • Hepatitis B Surface Antigens
  • Hepatitis B Vaccines