Abstract
An increasing number of patients undergo soft-tissue augmentation. The quality depends on the applied filler substance, the compliance of the patient and the physician. Long-term adverse reactions are referred to as nodules or granulomas. Nodules following degradable gels and polyacrylamide hydrogel are always caused by bacteria. Nodules following inert, hydrophobic silicone gel and combination gels may emerge years after the injection. They are often caused by a low-grade infection with ensuing enhanced fibrosis and treatment requires a specialist.
MeSH terms
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Acrylic Resins / administration & dosage
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Acrylic Resins / adverse effects*
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Biocompatible Materials / administration & dosage*
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Contraindications
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Face / surgery
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Granuloma / chemically induced
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Granuloma / pathology
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Humans
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Hydrogels / administration & dosage*
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Injections, Subcutaneous
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Polyhydroxyethyl Methacrylate / administration & dosage
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Polyhydroxyethyl Methacrylate / adverse effects
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Polymethyl Methacrylate / administration & dosage
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Polymethyl Methacrylate / adverse effects
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Silicone Gels / administration & dosage
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Silicone Gels / adverse effects*
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Surgery, Plastic / adverse effects*
Substances
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Acrylic Resins
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Biocompatible Materials
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Hydrogels
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Silicone Gels
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polyacrylamide gels
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Polyhydroxyethyl Methacrylate
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Polymethyl Methacrylate