Testicular microlithiasis: prevalence and risk of concurrent and interval development of testicular tumor in a referred population

Int Urol Nephrol. 2007;39(4):1177-81. doi: 10.1007/s11255-007-9203-0. Epub 2007 Jun 30.

Abstract

Aims: To identify prevalence of testicular microlithiasis on ultrasound in a referred population and risk of concurrent and interval testicular tumor development.

Methods: Retrospective review of our radiology database revealed 4363 scrotal ultrasounds were performed over a six-year period. Ultrasound findings were correlated with our hospital pathological database. The association of intratesticular microlithiasis and confirmed testicular cancers were assessed by means of a Fisher exact test.

Results: Testicular microlithiasis was identified in 32 of the 4259 patients (0.75% of screened population). In the same time period 83 testicular tumors were identified on initial scanning (2.00% of screened population). Three patients with tumor had coexisting microlithiasis (9.4% incidence), whilst a further two had interval development of tumor. The follow-up of the microlithiasis patients ranged from 3 to 72 months (mean 33.9 months, median 40 months).

Conclusions: Interval development of testicular tumor is a documented phenomenon. As the incidence in detection of microlithiasis increases secondary to advances in ultrasound technology, follow-up becomes financially prohibitive. We advocate regular self-examination as the primary follow-up of otherwise well patients with testicular microlithiasis.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Calculi / diagnostic imaging
  • Calculi / epidemiology*
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Referral and Consultation
  • Retrospective Studies
  • Risk Factors
  • Testicular Diseases / diagnostic imaging
  • Testicular Diseases / epidemiology*
  • Testicular Neoplasms / diagnostic imaging
  • Testicular Neoplasms / epidemiology*
  • Ultrasonography