Absence of nucleophosmin leukaemic mutants in B and T cells from AML with NPM1 mutations: implications for the cell of origin of NPMc+ AML

Leukemia. 2008 Jan;22(1):195-8. doi: 10.1038/sj.leu.2404857. Epub 2007 Jul 19.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Active Transport, Cell Nucleus
  • Acute Disease
  • B-Lymphocytes / metabolism*
  • B-Lymphocytes / pathology
  • Biopsy
  • Bone Marrow / metabolism
  • Cell Lineage
  • Cytoplasm / metabolism
  • Fluorescent Antibody Technique
  • Humans
  • Immunoenzyme Techniques
  • Leukemia, Myeloid / diagnosis
  • Leukemia, Myeloid / genetics*
  • Mutation*
  • Myeloid Cells
  • Nuclear Proteins / genetics*
  • Nucleophosmin
  • Phosphoproteins / genetics
  • Subcellular Fractions
  • T-Lymphocytes / metabolism*
  • T-Lymphocytes / pathology

Substances

  • NPM1 protein, human
  • Nuclear Proteins
  • Phosphoproteins
  • Nucleophosmin