Endoscopic bilateral metal stent placement for advanced hilar cholangiocarcinoma: a pilot study of a newly designed Y stent

Gastrointest Endosc. 2007 Aug;66(2):364-9. doi: 10.1016/j.gie.2006.12.061.

Abstract

Background: Although endoscopic stent placement is now generally accepted as a palliative method of treatment in unresectable hilar cholangiocarcinoma, exclusively endoscopic placement of bilateral metal stents has been considered very difficult and complex.

Objective: To evaluate the technical and clinical efficacy of endoscopic placement of dual, newly designed stents in a Y configuration.

Design: Prospective, uncontrolled, single center.

Setting: Tertiary referral university hospital.

Patients: Ten patients with unresectable hilar cholangiocarcinoma of Bismuth type II or higher.

Interventions: For bilateral metal stent placement, a biliary Y stent with central wide-open mesh was used exclusively at first. A second stent was placed into the contralateral hepatic duct through the central open mesh of the Y stent.

Main outcome measurement: Technical success, functional success, early complications, and short-term clinical outcome.

Results: Technical success was achieved in 8 of 10 patients (80%). Among 8 patients in whom bilateral stents were successfully placed by endoscopy, functional success was 100%, the early complication rate was 0%, and the stent occlusion rate was 25%. The median stent patency period was 217 days.

Limitations: Small number of patients, uncontrolled study, short-term follow-up period.

Conclusions: We described a technique for endoscopic bilateral metal stent placement by using the newly designed Y stent for advanced hilar cholangiocarcinoma that resulted in a high success rate of 80%.

MeSH terms

  • Aged
  • Alloys
  • Bile Duct Neoplasms / complications*
  • Bile Duct Neoplasms / therapy
  • Bile Ducts, Intrahepatic*
  • Cholangiocarcinoma / complications*
  • Cholangiocarcinoma / therapy
  • Cholestasis / etiology
  • Cholestasis / therapy*
  • Drainage
  • Endoscopy, Digestive System*
  • Female
  • Hepatic Duct, Common
  • Humans
  • Male
  • Middle Aged
  • Palliative Care*
  • Stents*

Substances

  • Alloys
  • nitinol