Abstract
We report a case of BK virus-induced tubulointerstitial nephritis in a child with acute lymphoblastic leukemia. Primary BK virus infection was exacerbated by chemotherapy-induced immunodeficiency. Careful administration of chemotherapy and anti-viral therapy prevented further damage. This diagnosis should be considered in children who experience renal dysfunction during cancer treatment.
Publication types
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Case Reports
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / adverse effects
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Antiviral Agents / therapeutic use
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BK Virus / isolation & purification*
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Biopsy, Needle
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Child, Preschool
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Female
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Follow-Up Studies
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Humans
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Immunohistochemistry
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Kidney Function Tests
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Nephritis, Interstitial / complications
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Nephritis, Interstitial / drug therapy
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Nephritis, Interstitial / virology*
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Polyomavirus Infections / complications
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Polyomavirus Infections / diagnosis*
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Polyomavirus Infections / therapy
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Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
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Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis*
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Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
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Risk Assessment
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Treatment Outcome
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Tumor Virus Infections / complications
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Tumor Virus Infections / diagnosis*
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Tumor Virus Infections / therapy