Abstract
Helicobacter pylori infection remains a significant global public health problem. Vaccine development against this infection appears to be feasible but has not yet delivered its promise in clinical trials. Efforts to improve current vaccination strategies would greatly benefit from a better molecular understanding of the mechanism of protection. Here, we review recent developments in this field.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Bacterial Vaccines / immunology*
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CD4-Positive T-Lymphocytes / immunology
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Disease Models, Animal
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Gastric Mucosa / immunology
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Gastric Mucosa / microbiology
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Gastrointestinal Diseases / immunology
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Gastrointestinal Diseases / microbiology*
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Gastrointestinal Diseases / prevention & control
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Helicobacter Infections / immunology*
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Helicobacter Infections / microbiology
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Helicobacter Infections / prevention & control
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Helicobacter pylori / immunology*
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Mice