Streptococcus pneumoniae isolates in healthy children attending day-care centers in 12 states in Mexico

Salud Publica Mex. 2007 Jul-Aug;49(4):249-55. doi: 10.1590/s0036-36342007000400004.

Abstract

Objective: The aim of this study was to determine the prevalence of asymptomatic nasopharyngeal carriage of Streptococcus pneumoniae, which is a major factor in the transmission of this bacterium.

Material and methods: Nasopharyngeal cultures were performed on children attending 32 day-care centers in 12 states in Mexico.

Results: Streptococcus pneumoniae was isolated from the nasopharynx of 829 out of 2,777(29.9%) subjects aged two months to six years. All children lived in urban areas and 80% spent more than six hours daily in a day-care center. Streptococcus pneumoniae serotypes most frequently identified were: 19F (23%), 6B (15.6%), 23F (11.2%) and 6A (14.9%). Thirty-six percent of the isolates were susceptible to penicillin.

Conclusions: Serotype distribution suggests the possible benefits that could be obtained from the heptavalent pneumococcal conjugate vaccine.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Child
  • Child Day Care Centers*
  • Child, Preschool
  • Data Interpretation, Statistical
  • Humans
  • Infant
  • Mexico
  • Microbial Sensitivity Tests
  • Nasopharynx / microbiology
  • Penicillins / pharmacology
  • Pneumococcal Infections / prevention & control
  • Pneumococcal Vaccines / administration & dosage
  • Serotyping
  • Streptococcus pneumoniae / drug effects
  • Streptococcus pneumoniae / isolation & purification*
  • Time Factors
  • Urban Population

Substances

  • Penicillins
  • Pneumococcal Vaccines