Real-time detection of lymphocytes binding on an antibody chip using SPR imaging

Lab Chip. 2007 Sep;7(9):1206-8. doi: 10.1039/b708292d. Epub 2007 Jun 22.

Abstract

We demonstrate the use of SPR imaging for the detection of site-specific binding of either B or T lymphocyte populations on an electrochemically-grafted antibody array.

Publication types

  • Evaluation Study

MeSH terms

  • Antibodies / immunology*
  • Cell Count / instrumentation*
  • Cell Count / methods
  • Computer Systems
  • Equipment Design
  • Equipment Failure Analysis
  • Immunoassay / instrumentation*
  • Immunoassay / methods
  • Lymphocytes / cytology*
  • Lymphocytes / immunology*
  • Microfluidic Analytical Techniques / instrumentation*
  • Microfluidic Analytical Techniques / methods
  • Surface Plasmon Resonance / instrumentation*
  • Surface Plasmon Resonance / methods

Substances

  • Antibodies