[Metastatic lesions to the pancreas. When is resection reasonable?]

Chirurg. 2008 Mar;79(3):241-8. doi: 10.1007/s00104-007-1390-9.
[Article in German]

Abstract

Background: The significance of pancreatic resection for pancreatic metastatic lesions has not yet been sufficiently investigated. A retrospective analysis of patients undergoing pancreatic resections for pancreatic metastases was conducted.

Material and methods: Twenty patients were resected due to metastatic lesions to the pancreas. Histopathological findings were: renal cell carcinoma (n=9), colon carcinoma (n=1), malignant schwannoma (n=2), leiomyosarcoma (n=2), teratocarcinoma (n=1), adenocarcinoma of the oesophagus (n=1), gallbladder carcinoma (n=1), malignant melanoma (n=1), gastrointestinal stromal tumor (n=1), and spindle cell tumor (n=1). Operative procedures were standard pancreaticoduodenectomy (n=6), pylorus-preserving pancreaticoduodenectomy (n=6), and distal pancreatectomy (n=8).

Result: The overall 5-year survival rate was 61%, for patients with renal cell carcinoma 100%.

Conclusion: Pancreatic metastasectomy is a reasonable therapeutic option in suited patients. Patients with pancreatic metastases of renal cell carcinoma achieved excellent prognoses after radical resection.

Publication types

  • English Abstract

MeSH terms

  • Aged
  • Chemotherapy, Adjuvant
  • Combined Modality Therapy
  • Female
  • Follow-Up Studies
  • Humans
  • Lymph Node Excision
  • Male
  • Middle Aged
  • Palliative Care
  • Pancreatectomy*
  • Pancreatic Neoplasms / diagnosis
  • Pancreatic Neoplasms / mortality
  • Pancreatic Neoplasms / secondary*
  • Pancreatic Neoplasms / surgery*
  • Survival Rate