Outcome after Fontan failure and takedown to an intermediate palliative circulation

Ann Thorac Surg. 2007 Sep;84(3):880-7. doi: 10.1016/j.athoracsur.2007.02.092.

Abstract

Background: Fontan takedown to an intermediate palliative circulation is an important treatment option for patients with acute or subacute failure of a Fontan circulation from a variety of causes. Little is known about the subsequent outcome of these patients or their potential candidacy for a second attempt at Fontan completion.

Methods: Patients followed up at Children's Hospital Boston who underwent takedown of a Fontan circulation to an intermediate palliative circulation within 1 year of Fontan completion were reviewed.

Results: Between 1979 and 2006, 53 patients underwent Fontan takedown at a median age of 2.3 years (range, 0.3 to 36.5 years). Takedown was performed during the Fontan procedure itself in 12 patients (22%), within the first postoperative month in 31(58%), and between 1 month and 1 year in 10 (18%). Overall, 29 patients (55%) survived the early period after takedown, and 19 ultimately underwent successful Fontan completion a median of 4.6 years after takedown; all but one was alive a median of 6.4 years later. Thirteen (68%) of the 19 had treatable abnormalities contributing to Fontan failure.

Conclusions: Fontan takedown can provide effective stabilization of the acutely or subacutely failing Fontan circulation, although a substantial number of patients die early despite Fontan takedown. Subjects surviving the perioperative period can often undergo uneventful redo Fontan. A thorough evaluation for treatable abnormalities should be performed in all patients with a failing Fontan circulation and in patients who undergo Fontan takedown.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Coronary Circulation*
  • Follow-Up Studies
  • Fontan Procedure / adverse effects*
  • Fontan Procedure / methods
  • Heart Transplantation
  • Humans
  • Infant
  • Pulmonary Artery / abnormalities
  • Retrospective Studies
  • Treatment Failure