Vorinostat and bortezomib significantly inhibit WT1 gene expression in MO7-e and P39 cell lines

Leukemia. 2008 Mar;22(3):628-31. doi: 10.1038/sj.leu.2404918. Epub 2007 Aug 30.
No abstract available

Publication types

  • Letter

MeSH terms

  • Antineoplastic Agents / pharmacology*
  • Boronic Acids / pharmacology*
  • Bortezomib
  • Cell Line, Tumor / metabolism
  • Down-Regulation / drug effects
  • Drug Screening Assays, Antitumor
  • Drug Synergism
  • Enzyme Inhibitors / pharmacology*
  • Gene Expression Regulation, Leukemic / drug effects*
  • Genes, Wilms Tumor / drug effects*
  • Humans
  • Hydroxamic Acids / pharmacology*
  • Leukemia, Megakaryoblastic, Acute / pathology
  • Leukemia, Myelomonocytic, Chronic / pathology
  • Megakaryocytes / drug effects
  • Megakaryocytes / metabolism
  • Neoplasm Proteins / biosynthesis*
  • Pyrazines / pharmacology*
  • Vorinostat
  • WT1 Proteins / biosynthesis*

Substances

  • Antineoplastic Agents
  • Boronic Acids
  • Enzyme Inhibitors
  • Hydroxamic Acids
  • Neoplasm Proteins
  • Pyrazines
  • WT1 Proteins
  • Vorinostat
  • Bortezomib