The Ni2+ binding properties of Helicobacter pylori NikR

Chem Commun (Camb). 2007 Sep 21:(35):3649-51. doi: 10.1039/b706025d. Epub 2007 Jun 28.

Abstract

The binding constants between Ni2+ and Helicobacterpylori NikR have been determined using isothermal titration microcalorimetry in order to rationalize the role of this protein as a nickel-dependent biological sensor.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / chemistry
  • Bacterial Proteins / metabolism*
  • Binding Sites
  • Helicobacter pylori / chemistry*
  • Nickel / metabolism*
  • Nickel / pharmacology
  • Protein Conformation
  • Repressor Proteins / chemistry
  • Repressor Proteins / metabolism*

Substances

  • Bacterial Proteins
  • NikR protein, Helicobacter pylori
  • Repressor Proteins
  • Nickel