The sensitivity of preoperative scanning in regional recurrence of papillary thyroid cancer

Otolaryngol Head Neck Surg. 2007 Sep;137(3):412-5. doi: 10.1016/j.otohns.2007.04.010.

Abstract

Background: The treatment of patients with regionally recurrent papillary carcinoma of the thyroid is a matter of controversy. Radioactive nodal picking was proposed as an alternative to neck dissection in these patients.

Methods: We analyzed neck dissection specimens in 20 patients with PTC and compared the results to preoperative total-body scan (TBS) following a therapeutic dose of I(131)and ultrasonographic findings.

Results: Eighteen patients underwent paratracheal neck dissection and 10 patients had a lateral neck dissection. Preoperative TBS detected the correct number of positive nodes in only 1 patient (5%) and the correct number of patients with positive nodes in 6/20 (30%) of the patients. US detected 32/98 positive nodes (36%) and 20/20 (100%) of the patients. Prediction of the number of positive nodes for both TBS and US was low (5% and 10%, respectively).

Conclusions: Preoperative TBS and/or US cannot satisfactorily predict metastatic lymph node involvement and cannot safely delineate limited surgery to replace formal neck dissection in patients with regionally recurrent PTC.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Aged
  • Carcinoma, Papillary / diagnosis*
  • Carcinoma, Papillary / secondary*
  • Carcinoma, Papillary / therapy
  • Female
  • Humans
  • Iodine Radioisotopes / therapeutic use
  • Male
  • Middle Aged
  • Neck Dissection
  • Predictive Value of Tests
  • Preoperative Care
  • Radiopharmaceuticals / therapeutic use
  • Thyroid Neoplasms / pathology*
  • Thyroid Neoplasms / therapy
  • Whole Body Imaging*

Substances

  • Iodine Radioisotopes
  • Radiopharmaceuticals