PCR real time assays for the early detection of BKV-DNA in immunocompromised patients

New Microbiol. 2007 Jul;30(3):275-8.

Abstract

Testing for viral BKV-DNA in urine is a non-invasive early detection and monitoring tool in the diagnostic of BKV-related pathologies: quantitative analysis by Real-Time PCR can provide useful information in addition to cytologic analysis, although our study suggests that high BKV viruria is not necessarily associated with kidney or bladder damage.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • BK Virus / isolation & purification*
  • BK Virus / physiology
  • Child
  • Child, Preschool
  • DNA, Viral / urine*
  • Early Diagnosis
  • Female
  • Humans
  • Immunocompromised Host*
  • Infant
  • Kidney Diseases / diagnosis*
  • Kidney Diseases / virology
  • Kidney Transplantation
  • Male
  • Middle Aged
  • Polymerase Chain Reaction
  • Polyomavirus Infections / diagnosis*
  • Sensitivity and Specificity
  • Tumor Virus Infections / diagnosis*
  • Tumor Virus Infections / virology
  • Virus Activation

Substances

  • DNA, Viral