Evaluation of the nitrite and leukocyte esterase activity tests for the diagnosis of acute symptomatic urinary tract infection in men

Jeanne Juliette Koeijers; Alfons G H Kessels; Sita Nys; A Bartelds; G Donker; Ellen E Stobberingh; Annelies Verbon

doi:10.1086/521254

Evaluation of the nitrite and leukocyte esterase activity tests for the diagnosis of acute symptomatic urinary tract infection in men

Clin Infect Dis. 2007 Oct 1;45(7):894-6. doi: 10.1086/521254. Epub 2007 Aug 21.

Authors

Jeanne Juliette Koeijers¹, Alfons G H Kessels, Sita Nys, A Bartelds, G Donker, Ellen E Stobberingh, Annelies Verbon

Affiliation

¹ Department of Internal Medicine, University Hospital Maastricht, The Netherlands.

PMID: 17806056
DOI: 10.1086/521254

Abstract

For 422 male patients with symptoms indicative of a urinary tract infection, nitrite and leukocyte esterase activity dipstick test results were compared with results of culture of urine samples. The positive predictive value of a positive nitrite test result was 96%. Addition of results of the leukocyte esterase test did not improve the diagnostic accuracy of the nitrite test.

Publication types

Evaluation Study
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Aged
Aged, 80 and over
Carboxylic Ester Hydrolases / urine*
Colony Count, Microbial
Humans
Male
Middle Aged
Nitrites / urine*
Predictive Value of Tests
Reagent Strips*
Sensitivity and Specificity
Urinary Tract Infections / diagnosis*
Urinary Tract Infections / enzymology
Urinary Tract Infections / microbiology
Urine / microbiology

Substances

Nitrites
Reagent Strips
leukocyte esterase
Carboxylic Ester Hydrolases