Successful treatment with rituximab in a patient with an acquired factor V inhibitor

Am J Hematol. 2008 Feb;83(2):163-4. doi: 10.1002/ajh.21056.

Abstract

Rituximab has already been successfully used to treat immune-mediated bleeding disorders such as acquired factor VIII inhibitor. We report here a case of severe acquired factor V (FV) inhibitor deficiency due to FV inhibitor which has been dramatically improved after rituximab.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antibodies, Monoclonal / therapeutic use*
  • Antibodies, Monoclonal, Murine-Derived
  • Factor V / drug effects
  • Factor V / metabolism
  • Factor V Deficiency / drug therapy*
  • Factor V Deficiency / etiology
  • Female
  • Humans
  • Immunologic Factors / therapeutic use*
  • Prothrombin Time
  • Rituximab

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Murine-Derived
  • Immunologic Factors
  • Rituximab
  • Factor V