Long-term experience with conservative surgery of renal tumors. Surgical technique, complications, results, DNA-cytometry

Scand J Urol Nephrol Suppl. 1991:138:207-13.

Abstract

The surgical technique, course and complications were analysed in 123 patients in whom a kidney tumor had been enucleated. Fifty-seven enucleated tumors were available for image analysis DNA-cytometry. In 49 patients there was an imperative indication for an organ-preserving operation, because nephrectomy would have made dialysis obligatory. In 74 patients with a healthy contralateral kidney the tumor was enucleated by choice. Thirty-five of 49 patients with an imperative indication are without sign of tumor progression after a mean follow-up of 4.5 years. In two patients there was a recurrence after 4 and 5 years, respectively, requiring a second organ-preserving operation. In one further patient there is a suspicion of multiple small tumor lesions 2 years after the first operation. Known metastases were present in 3 of 6 patients who died of their tumors. Sixty-eight of 74 patients operated on electively are without signs of tumor progression after a mean follow-up period of 3.3 years. One patient died from tumor metastases. Two patients had tumor recurrence, requiring nephrectomy and enucleation, respectively.

MeSH terms

  • Adult
  • Aged
  • DNA, Neoplasm / genetics*
  • Female
  • Humans
  • Kidney Neoplasms / genetics
  • Kidney Neoplasms / pathology
  • Kidney Neoplasms / surgery*
  • Male
  • Methods
  • Middle Aged
  • Ploidies
  • Postoperative Complications
  • Prognosis

Substances

  • DNA, Neoplasm