When a former breast cancer patient asks for pregnancy, several questions have to be considered. The physician has to answer and counsel clearly and honestly his/her patient regarding the possibilities, risks and specificities associated with a pregnancy in this case. The individual risk of relapse should be considered, together with individual predictive factors and theoretical benefits of specific prolonged treatments such as hormone therapy. Both risks associated with the pregnancy itself and with the modification of treatment schemes have to be evaluated. Risks related to Assisted reproductive techniques when indicated, should also be considered and explained. Potential foetal risks should be explained too. The aim of this review is to summarize the current knowledge and then available tools that the physician can use to help the couple making decision regarding subsequent pregnancy.