Validation of a PCR-oligochromatography test for detection of Trypanozoon parasites in a multicenter collaborative trial

J Clin Microbiol. 2007 Nov;45(11):3785-7. doi: 10.1128/JCM.01244-07. Epub 2007 Sep 19.

Abstract

A PCR-oligochromatography test for diagnosis of human and animal trypanosomiasis was evaluated through a multicenter ring trial with six laboratories testing a set of 21 blinded samples, resulting in qualitative data (positive or negative). Results showed an intralaboratory repeatability (accordance) of 88.7% (credible interval [CI], 84.4 to 92.5%) and an interlaboratory repeatability (concordance) of 88.1% (CI, 84.3 to 92.3%).

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Animals
  • DNA, Protozoan / analysis
  • Polymerase Chain Reaction / methods*
  • Reproducibility of Results
  • Trypanosoma / genetics
  • Trypanosoma / isolation & purification*

Substances

  • DNA, Protozoan