Synthesis and characterization of hydroxy-functionalized models for the active site in Fe-only-hydrogenases

Chem Biodivers. 2007 Sep;4(9):2138-48. doi: 10.1002/cbdv.200790171.

Abstract

The reactions of DL-1,4-disulfanylbutane-2,3-diol and 1,3-disulfanylpropan-2-ol with dodecacarbonyltriiron have been investigated. As main products, the iron complexes 1 and 2 were isolated and characterized by spectroscopic methods, as well as single crystal X-ray analysis. Additionally, the unusually large bond angles in the dithiolato bridge was investigated via density-functional theory (DFT) calculations. Moreover, the electrochemical features have been studied by cyclic voltammetry.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Binding Sites
  • Catalysis
  • Crystallography, X-Ray
  • Hydrogenase / chemistry*
  • Iron-Sulfur Proteins / chemistry*
  • Models, Chemical
  • Molecular Structure
  • Organometallic Compounds / chemistry*

Substances

  • Iron-Sulfur Proteins
  • Organometallic Compounds
  • iron hydrogenase
  • Hydrogenase