Effect of leucovorin on 5-fluorouracil induced inhibition of thymidylate synthase in patients with colon cancer

Adv Exp Med Biol. 1991:309A:131-4. doi: 10.1007/978-1-4899-2638-8_29.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Colonic Neoplasms / drug therapy*
  • Colonic Neoplasms / enzymology
  • Colonic Neoplasms / pathology
  • Female
  • Fluorouracil / administration & dosage
  • Fluorouracil / therapeutic use*
  • Humans
  • Leucovorin / administration & dosage
  • Leucovorin / therapeutic use*
  • Male
  • Middle Aged
  • Rectal Neoplasms / drug therapy*
  • Rectal Neoplasms / enzymology
  • Rectal Neoplasms / pathology
  • Thymidylate Synthase / antagonists & inhibitors*

Substances

  • Thymidylate Synthase
  • Leucovorin
  • Fluorouracil