Abstract
Microbial transformation of the cancer chemopreventive agent, decursin (1) with Sepedonium chrysospermem (ATCC 13378) yielded two metabolites, (+)-decursinol (2) and (-)-cis-decursidinol (3). The structures were established by spectroscopic data.
MeSH terms
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Anticarcinogenic Agents / pharmacology*
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Benzopyrans / pharmacology*
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Butyrates / pharmacology*
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Cells, Cultured
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Hypocreales / drug effects*
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Hypocreales / metabolism
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Metabolic Networks and Pathways / drug effects*
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Metabolic Networks and Pathways / physiology
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Pyranocoumarins / pharmacology*
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Spectrum Analysis
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Stereoisomerism
Substances
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Anticarcinogenic Agents
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Benzopyrans
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Butyrates
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Pyranocoumarins
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decursin