Sarcoidosis accompanied by systemic lupus erythematosus and autoimmune hepatitis

Intern Med. 2007;46(19):1657-61. doi: 10.2169/internalmedicine.46.0201. Epub 2007 Oct 1.

Abstract

A 52-year-old woman was admitted to our hospital for further examination of blurred vision, abnormal lung shadows and an elevated level of angiotensin-converting enzyme. Sarcoidosis was suspected, however, careful history taking revealed the existence of photosensitivity and polyarthralgia. Laboratory tests showed lymphocytopenia, liver dysfunction, hypergammaglobulinemia, and positive anti-nuclear, anti-double stranded DNA and anti-smooth muscle antibodies. Liver biopsy examination showed chronic active hepatitis. She was diagnosed with the triplex of sarcoidosis, systemic lupus erythematosus and autoimmune hepatitis. Marked improvement was noted after corticosteroid therapy.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Autoantibodies / blood
  • Biopsy
  • Female
  • Hepatitis, Autoimmune / complications*
  • Hepatitis, Autoimmune / diagnosis
  • Humans
  • Liver / pathology
  • Lupus Erythematosus, Systemic / complications*
  • Lupus Erythematosus, Systemic / diagnosis
  • Middle Aged
  • Sarcoidosis / complications*
  • Sarcoidosis / diagnosis

Substances

  • Adrenal Cortex Hormones
  • Autoantibodies