Irinotecan-induced central nervous system toxicity. Report on two cases and review of the literature

Acta Oncol. 2008;47(5):974-8. doi: 10.1080/02841860701666089.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Review

MeSH terms

  • Adult
  • Antiemetics / therapeutic use
  • Antineoplastic Agents, Phytogenic / adverse effects*
  • Ataxia / chemically induced
  • Camptothecin / adverse effects
  • Camptothecin / analogs & derivatives*
  • Capecitabine
  • Central Nervous System / drug effects*
  • Colorectal Neoplasms / pathology
  • Colorectal Neoplasms / secondary*
  • Cytotoxins / adverse effects
  • Deoxycytidine / administration & dosage
  • Deoxycytidine / analogs & derivatives
  • Dexamethasone / therapeutic use
  • Dysarthria / chemically induced*
  • Female
  • Fluorouracil / administration & dosage
  • Fluorouracil / analogs & derivatives
  • Granisetron / therapeutic use
  • Humans
  • Irinotecan
  • Male
  • Middle Aged
  • Organoplatinum Compounds / administration & dosage
  • Oxaliplatin
  • Sarcoma, Small Cell / drug therapy*
  • Sarcoma, Small Cell / secondary
  • Serotonin Antagonists / therapeutic use
  • Topoisomerase I Inhibitors

Substances

  • Antiemetics
  • Antineoplastic Agents, Phytogenic
  • Cytotoxins
  • Organoplatinum Compounds
  • Serotonin Antagonists
  • Topoisomerase I Inhibitors
  • Oxaliplatin
  • Deoxycytidine
  • Capecitabine
  • Irinotecan
  • Dexamethasone
  • Fluorouracil
  • Granisetron
  • Camptothecin