Abstract
We conducted a retrospective cohort study of children with catheter-associated bloodstream infections (BSIs) due to Escherichia coli and/or Klebsiella. Risk factors for poor outcome (ie, death or recurrence of infection) were receipt of mechanical ventilation (adjusted odds ratio [aOR], 4.6 [95% confidence interval {CI}, 1.39-16.30]) and receipt of total parenteral nutrition (aOR, 3.5 [95% CI, 1.1-10.8]). A significant proportion of children with catheter-associated BSI were treated successfully without catheter removal.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Anti-Bacterial Agents / therapeutic use*
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Catheterization, Central Venous / adverse effects*
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Child
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Child, Preschool
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Cohort Studies
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Escherichia coli Infections / blood
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Escherichia coli Infections / etiology*
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Escherichia coli Infections / therapy
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Escherichia coli*
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Female
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Hospital Mortality
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Humans
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Infant
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Infant, Newborn
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Klebsiella Infections / blood
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Klebsiella Infections / etiology*
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Klebsiella Infections / therapy
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Male
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Parenteral Nutrition, Total
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Recurrence
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Respiration, Artificial
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Sepsis / etiology*
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Sepsis / microbiology
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Sepsis / therapy
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Treatment Outcome