Ameloblastic carcinoma of the maxilla: case report and review of the literature

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Dec;104(6):e17-24. doi: 10.1016/j.tripleo.2007.05.026. Epub 2007 Oct 17.

Abstract

Material and methods: A case of ameloblastic carcinoma of the maxilla arising in a 90-year-old patient is presented along with a review of 65 other cases of the international literature.

Results: The median age was 44 years with a predominance of men (42/66). The maxilla was concerned in almost one third of cases (21/66). Twenty patients died of disease after a median time of 60 months. Fifteen patients died with metastatic spread in the lung, brain, or bones; the others were due to a local recurrence. The specific survival rate was 68.7% at 5 years.

Conclusion: Ameloblastic carcinoma is a rare entity of odontogenic tumors that exhibits malignant histologic features in the primary site. Specific mortality, estimated at 31.3% at 5 years, was generally due to a metastatic spread.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged, 80 and over
  • Ameloblastoma / mortality
  • Ameloblastoma / pathology*
  • Ameloblastoma / surgery
  • Diagnosis, Differential
  • Humans
  • Jaw, Edentulous / diagnostic imaging
  • Jaw, Edentulous / pathology
  • Jaw, Edentulous / surgery
  • Male
  • Maxillary Neoplasms / mortality
  • Maxillary Neoplasms / pathology*
  • Maxillary Neoplasms / surgery
  • Radiography
  • Survival Analysis