Abstract
This paper presents the modeling of the electrical properties of bioactivated nanopores, customized nanopore devices with a biological macromolecule attached in the pore as the probe. These devices are capable of detecting and analyzing interactions between the attached biomolecule and the molecules in the analyte at a single molecule level.
Publication types
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Evaluation Study
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Biological Assay / instrumentation
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Biological Assay / methods
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Biopolymers / analysis
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Biopolymers / chemistry*
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Biosensing Techniques / instrumentation*
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Biosensing Techniques / methods
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Computer Simulation
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Computer-Aided Design
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Electrochemistry / instrumentation
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Electrochemistry / methods
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Equipment Design
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Equipment Failure Analysis
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Membranes, Artificial*
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Microelectrodes
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Models, Chemical*
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Molecular Probe Techniques / instrumentation*
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Nanostructures / chemistry*
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Nanostructures / ultrastructure*
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Porosity
Substances
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Biopolymers
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Membranes, Artificial