Cytokine-producing activity of bone marrow erythrokaryocytes and its regulation under normal conditions

V V Denisova; A D Kulagin; I A Lisukov; I V Kryuchkova; S A Sizikova; S V Sennikov; V A Kozlov

doi:10.1007/s10517-007-0055-5

Cytokine-producing activity of bone marrow erythrokaryocytes and its regulation under normal conditions

Bull Exp Biol Med. 2007 Feb;143(2):218-21. doi: 10.1007/s10517-007-0055-5.

Authors

V V Denisova¹, A D Kulagin, I A Lisukov, I V Kryuchkova, S A Sizikova, S V Sennikov, V A Kozlov

Affiliation

¹ Institute of Clinical Immunology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk. [email protected]

PMID: 17970206
DOI: 10.1007/s10517-007-0055-5

Abstract

We showed that inhibition of cytokine production by bone marrow adherent cells and their soluble products is a mechanism of regulation of cytokine-producing activity of bone marrow erythrokaryocytes under normal conditions.

MeSH terms

Bone Marrow Cells / metabolism*
Chemotactic Factors / metabolism
Cytokines / metabolism*
Erythrocytes / metabolism*
Glycophorins / metabolism
Granulocyte Colony-Stimulating Factor / metabolism
Granulocyte-Macrophage Colony-Stimulating Factor / metabolism
Humans
Interferon-gamma / metabolism
Interleukin-10 / metabolism
Interleukin-13 / metabolism
Interleukin-17 / metabolism
Interleukin-1beta / metabolism
Interleukin-4 / metabolism
Interleukin-6 / metabolism
Interleukin-8 / metabolism
Macrophage Inflammatory Proteins / metabolism
Tumor Necrosis Factor-alpha / metabolism

Substances

Chemotactic Factors
Cytokines
Glycophorins
Interleukin-13
Interleukin-17
Interleukin-1beta
Interleukin-6
Interleukin-8
Macrophage Inflammatory Proteins
Tumor Necrosis Factor-alpha
Interleukin-10
Granulocyte Colony-Stimulating Factor
Interleukin-4
Interferon-gamma
Granulocyte-Macrophage Colony-Stimulating Factor