Bearing in mind that diabetes mellitus is frequently associated with secondary hyperlipoproteinemias, the objective of our study was to examine the possibilities for correction of lipid metabolism disorders in obese diabetics by introducing 1500 cal (6200 kJ) dietetic regimen. The study included a group of 20 obese male subjects (BMI>30) suffering from type 2 diabetes mellitus, aged from 28 up to 62 years. During 6 months follow-up, the participants subjects to antidiabetic diet regimen reduced their body weight and significantly lowered BMI (p<0.01). For the evaluation of lipids status serum concentration of cholesterol, triglycerides, LDL, VLDL, HDL atthe beginning of the study and after 6 months follow-up period were determined. The results obtained showed the significant decrease of cholesterol (p<0.01), tryglicerides (p<0.01), LDL (p<0.01) levels and the increase of HDL (p<0.01) level in the sera of the diabetics studies.