Multidomain targeting generates a high-affinity thrombin-inhibiting bivalent aptamer

Chembiochem. 2007 Dec 17;8(18):2223-6. doi: 10.1002/cbic.200700535.
No abstract available

MeSH terms

  • Aptamers, Nucleotide / chemistry
  • Aptamers, Nucleotide / metabolism*
  • Base Sequence
  • Enzyme Inhibitors / chemistry
  • Ligands
  • Models, Molecular
  • Molecular Sequence Data
  • Thrombin / antagonists & inhibitors
  • Thrombin / metabolism*

Substances

  • Aptamers, Nucleotide
  • Enzyme Inhibitors
  • Ligands
  • Thrombin