The use of patient-controlled epidural fentanyl in elderly patients

Anaesthesia. 2007 Dec;62(12):1246-50. doi: 10.1111/j.1365-2044.2007.05256.x.

Abstract

We studied whether delivering postoperative analgesia, using a patient-controlled epidural analgesia (PCEA) device was effective and safe in elderly patients. We enrolled 40 patients aged > 65 years (elderly group) and 40 patients aged 20-64 years (young group) scheduled for elective major abdominal surgery. PCEA infusion was started following completion of surgery. Mean (SD) fentanyl consumption (10.7 (3.7) compared with 10.5 (2.7) microg.kg(-1), p = 0.76) and number of times patients pressed the bolus switch (32 (36) compared with 44 (38), p = 0.16) during the first 24 h postoperatively were similar in the two groups. Pain scores, which were similar in both groups at rest, were significantly lower in the elderly on coughing (at 24 h, p < 0.05). In addition, average pain scores were similar at the time of PCEA bolus demands in the two groups. Elderly and young adult patients therefore required similar amounts of patient-controlled epidural fentanyl to produce satisfactory pain relief.

Publication types

  • Evaluation Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abdomen / surgery
  • Adult
  • Age Factors
  • Aged
  • Analgesia, Patient-Controlled* / adverse effects
  • Analgesics, Opioid / administration & dosage*
  • Analgesics, Opioid / adverse effects
  • Body Weight
  • Cough / complications
  • Drug Administration Schedule
  • Female
  • Fentanyl / administration & dosage*
  • Fentanyl / adverse effects
  • Humans
  • Male
  • Middle Aged
  • Pain Measurement / methods
  • Pain, Postoperative / drug therapy*
  • Pain, Postoperative / etiology

Substances

  • Analgesics, Opioid
  • Fentanyl