Acute renal failure due to acute tubular necrosis caused by direct invasion of Orientia tsutsugamushi

J Clin Microbiol. 2008 Apr;46(4):1548-50. doi: 10.1128/JCM.01040-07. Epub 2007 Nov 14.

Abstract

We describe a scrub typhus patient with acute renal failure for whom a diagnosis was made based on serology as well as immunohistochemical (IHC) staining and an electron microscopic examination (EM) of a renal biopsy specimen. For our case, we demonstrated by IHC staining and EM that renal failure was caused by acute tubular necrosis due to a direct invasion of Orientia tsutsugamushi.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury / etiology*
  • Acute Kidney Injury / microbiology
  • Acute Kidney Injury / pathology
  • Adult
  • Humans
  • Immunohistochemistry
  • Kidney Tubular Necrosis, Acute / etiology
  • Kidney Tubular Necrosis, Acute / microbiology*
  • Kidney Tubular Necrosis, Acute / pathology
  • Male
  • Microscopy, Electron
  • Orientia tsutsugamushi / isolation & purification
  • Orientia tsutsugamushi / pathogenicity*
  • Scrub Typhus / complications*
  • Scrub Typhus / microbiology