Abstract
A series of novel 2-alkoxy- and 2-aryloxyiminoalkyl trifluoromethanesulfonanilide derivatives have shown significant in vitro parasiticidal activity against the ectoparasites Ctenocephalides felis and Rhipicephalus sanguineus. A number of these compounds also displayed significant in vitro endoparasite activity against the nematode Haemonchus contortus.
MeSH terms
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Animals
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Antiparasitic Agents / chemistry*
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Antiparasitic Agents / pharmacology*
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Haemonchus / drug effects
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Rhipicephalus sanguineus / drug effects*
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Siphonaptera / drug effects*
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Structure-Activity Relationship
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Sulfonamides / chemistry*
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Sulfonamides / pharmacology*
Substances
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Antiparasitic Agents
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Sulfonamides
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trifluoromethanesulfonanilide